Liverpool Head & Neck Centre

Terry Jones

Professor Terry Jones

Director LHNC/ Director of R&I LUHFT

I completed my undergraduate education at the University of London, completing a BSc (Hons) degree in Microbiology and Molecular Biology at Queen Mary College before studying medicine at St Bartholomew’s Hospital Medical College, graduating in 1993. 

I completed my surgical training in Otorhinolaryngology / Head and Neck Surgery (ORL-HNS) in Liverpool, during which time I developed a sub-specialist interest in Head and Neck surgical oncology. 

I was appointed to an NHS consultant post at University Hospital Aintree (UHA) in 2003, switching to a Clinical Senior Lecturer post at the University of Liverpool in 2006. I was subsequently appointed to a Readership in 2010 and a Personal Chair in Head and Neck Surgery in 2011.

In 2018, Liverpool Head and Neck Centre (LHNC) was launched and I was appointed as the inaugural Director. LHNC is a formal collaboration between Liverpool University Hospitals NHS Foundation Trust (LUHFT), Clatterbridge Cancer Centre NHS Foundation Trust (CCC), The Walton Centre NHS Foundation Trust and the University of Liverpool and comprises one of the largest clinical research facilities for H&N cancer in the world, comprising >200 clinicians & researchers to deliver research-led improvements in patient care. 

In addition to the Directorship of LHNC, I am Director of Research and Innovation for LUHFT, National Lead for the Genomics England Head and Neck Clinical Interpretation Partnership and a Non-Executive Director of CCC.

My main clinical interests related to function-sparing cancer surgery. In particular, the use of transoral laser techniques to remove cancers of the larynx, oropharynx and hypopharynx, thereby leaving patients with better speech and swallowing function after surgery. With colleagues, we have developed, in Liverpool, one the largest transoral laser microsurgery practice for the removal of head and neck cancers in the world.

    1. Basic/translational research: which focusses of the differential treatment response seen between Human papillomavirus +ve and –ve oropharyngeal squamous cell carcinomas. 

    2. Early and late phase Clinical Trials: Joint Chief Investigator respectively for three CRUK funded H&N studies: PATHOS, PATHOS-T & EORTC 1420 

    3. Clinical outcomes research: with a particular interest in swallowing and voice outcomes following transoral laser microsurgery

    4. Cancer Inequalities: and their impact on incidence and outcome for patients with head and neck cancer

  • For further details, including my publication record, please see:

  • 2021:

    Schache, A. G., Shaw, R., Ho, M. W. S., Winter, S. C., Glasbey, J., Ganly, I., . . . SICO, I. S. S. O. (2021). Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery. BJS OPEN, 5(6). doi:10.1093/bjsopen/zrab112

    Shrwani, K., Sharma, R., Krishnan, M., Jones, T., Mayora-Neto, M., Cantoni, D., . . . Zhang, Q. (2021). Detection of Serum Cross-Reactive Antibodies and Memory Response to SARS-CoV-2 in Prepandemic and Post-COVID-19 Convalescent Samples. JOURNAL OF INFECTIOUS DISEASES, 224(8), 1305-1315. doi:10.1093/infdis/jiab333

    Wilkie, M. D., Anaam, E. A., Lau, A. S., Rubbi, C. P., Vlatkovic, N., Jones, T. M., &
    Boyd, M. T. (2021) Metabolic Plasticity and Combinatorial Radiosensitisation
    Strategies in Human Papillomavirus-Positive Squamous Cell Carcinoma of the Head
    and Neck Cell Lines. Cancers, 13(19), 4836. doi:10.3390/cancers13194836

    Sharwani, K., Sharma, R., Krishnan, M., Jones, T., Mayora-Neto, M., Cantoni, D., . . . Zhang, Q. (2021). Detection of serum cross-reactive antibodies and memory response to SARS-CoV-2 in pre-pandemic and post-COVID-19 convalescent samples. The Journal of infectious diseases. doi:10.1093/infdis/jiab333

    Wilkie, M. D., Gaskell, P., Hall, B., Jones, T. M., & Kinshuck, A. J. (2021). Emergency presentations of head and neck cancer: Our experience in the wake of the COVID-19 pandemic. Clinical Otolaryngology. doi:10.1111/coa.13821

    Saulters, E., Woolley, J. F., Varadarajan, S., Jones, T. M., & Dahal, L. N. (2021). STINGing viral tumours: What we know from head and neck cancers. Cancer research. doi:10.1158/0008-5472.can-21-0785

    Milinis, K., Gaskell, P., Lau, A., Lancaster, J., & Jones, T. (2021). Early versus late oral feeding following total (pharyngo)laryngectomy: Systematic review and meta-analysis. Head and Neck-Journal for The Sciences and Specialties of The Head and Neck, 43(4), 1359-1368. doi:10.1002/hed.26616

    Glasbey, J. C., Omar, O., Nepogodiev, D., Minaya-Bravo, A., Bankhead-Kendall, B. K., Fiore, M., . . . SICO, I. S. S. O. (2021). Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. British Journal of Surgery, 108(1), 88-96. doi:10.1093/bjs/znaa051

    Glasbey, J. C., Nepogodiev, D., Simoes, J. F. F., Omar, O., Li, E., Venn, M. L., . . . Collaborative, C. (2021). Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study. Journal of Clinical Oncology, 39(1), 66-+. doi:10.1200/JCO.20.01933



    Rogers, Simon N; Allmark, Christine; Bekiroglu, Fazilet; Edwards, Rhiannon Tudor; Fabbroni, Gillon; Flavel, Robert; Highet, Victoria; Ho, Michael WS; Humphris, Gerald M; Jones, Terry M; Khattak, Owais; Lancaster, Jeffrey; Loh, Christopher; Lowe, Derek; Lowies, Cher; Macareavy, Dominic; Moor, James; Ong, TK; Prasai, A; Roland, Nicholas; Semple, Cherith; Spencer, Llinos Haf; Tandon, Sank; Thomas, Steven J; Schache, Andrew; Shaw, Richard J; Kanatas, Anastasios, (2020). Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: main results of a cluster preference randomised controlled trial. European Archives of Oto-Rhino-Laryngology. doi:10.1007/s00405-020-06533-3 

    C. Lucy Dalton, Kristijonas Milinis, David Houghton, Paul Ridley, Katharine Davies, Richard Williams, David Hamilton, Mark D. Wilkie, Anne Markey, Kim Clarke, Matthew Lofthouse, Timothy R. Helliwell, Asterios Triantafyllou, Jennifer Rodrigues, Krishna Bheemireddy, Rebecca Hanlon, Hulya Wieshmann, Anoop Haridass, Caroline Brammer, David Husband, Aditya Shenoy, Christopher Loh, Nicholas J. Roland, Fazilet Bekiroglu, Sankalap Tandon, Jeffrey Lancaster, Terence M. Jones (2020). Transoral laser microsurgery and radiotherapy for oropharyngeal squamous cell carcinoma: Equitable survival and enhanced function compared with contemporary standards of care. EJSO, 46(11), 2042-2049. doi:10.1016/j.ejso.2020.06.045

    Wilkie, Mark D.; Chudek, Dorota A.; Flynn, Christian D.; Gaskell, Peter; Loh, Christopher; Tandon, Sankalap; Roland, Nicholas J.; Jones, Terence M.; Lancaster, Jeffrey (2020). Outcomes and prognosticators in regionally recurrent cutaneous squamous cell carcinoma of the head and neck. EJSO, 46(11), 2035-2041. doi:10.1016/j.ejso.2020.07.035

    Wilkie, M. D., Anaam, E. A., Lau, A. S., Rubbi, C. P., Jones, T. M., Boyd, M. T., & Vlatković, N. (2020). TP53 mutations in head and neck cancer cells determine the Warburg phenotypic switch creating metabolic vulnerabilities and therapeutic opportunities for stratified therapies. Cancer Letters, 478, 107-121. doi:10.1016/j.canlet.2020.02.032

    Masterson, Liam; Howard, James; Gonzalez-Cruz, Jazmina; Jackson, Christopher; Barnett, Catherine; Overton, Lewis; Liu, Howard; Ladwa, Rahul; Simpson, Fiona; McGrath, Margie; Wallwork, Ben; Jones, Terry; Ottensmeier, Christian; Chua, Melvin L.K.; Perry, Chris; Khanna, Rajiv; Panizza, Benedict; Porceddu, Sandro; Lechner, Matt. (2020). Immune checkpoint inhibitors in advanced nasopharyngeal carcinoma: Beyond an era of chemoradiation?. International Journal of Cancer, 146(8), 2305-2314. doi:10.1002/ijc.32869

    Robinson, Max; O'Hara, James; Siddiq, Somiah; Jones, Terry M.; Paleri, Vinidh; Sandison, Ann; Thavaraj, Selvam. . (2020). Trans-oral robotic surgery for oropharyngeal cancer: implications for pathologists. Diagnostic Histopathology, 26(4), 181-187. doi:10.1016/j.mpdhp.2020.01.005

    Ghazal Asswad, Randa; Alvi, Sirhan; Davies, Katharine; Jones, Terry M.; Hamilton, David W.; Brammer, Caroline; Lancaster, Jeffrey; Loh, Christopher; Tandon, Sankalap; Roland, N (2020). The role of multidisciplinary decision making in oropharyngeal cancer: do we follow guidelines and are treatment decisions being implemented? European Archives of Oto-Rhino-Laryngology, 277(3), 947-952. doi:10.1007/s00405-019-05781-2

    Craig, Stephanie G; Anderson, Lesley A; Moran, Michael; Graham, Laura; Currie, Keith; Rooney, Keith; Robinson, Max; Bingham, Victoria; Cuschieri, Kate S; McQuaid, Stephen; Schache, Andrew G; Jones, Terry M; McCance, Dennis; Salto-Tellez, Manuel; McDade, Simon S; James, Jacqueline A (2020). Comparison of Molecular Assays for HPV Testing in Oropharyngeal Squamous Cell Carcinomas: A Population-Based Study in Northern Ireland. Cancer Epidemiology, Biomarkers & Prevention, 29(1), 31-38. doi:10.1158/1055-9965.epi-19-0538



    Jean-Jacques Stelmes, Vincent Gregoire, Vincent Vander Poorten, Wojciech Golusiñski, Mateusz Szewczyk, Terry Jones, Mohssen Ansarin, Martina A. Broglie, Roland Giger, Jens Peter Klussmann, Mererid Evans, Jean Bourhis, C. René Leemans, Giuseppe Spriano, Andreas Dietz, Keith Hunter, Frank Zimmermann, Ingeborg Tinhofer, Joanne M. Patterson, Silvana Quaglini, Anne-Sophie Govaerts, Catherine Fortpied, Christian Simon (2019). Organ Preservation and Late Functional Outcome in Oropharyngeal Carcinoma: Rationale of EORTC 1420, the "Best of" Trial. Frontiers in Oncology, 9. doi:10.3389/fonc.2019.00999

    Hargreaves, S., Beasley, M., Hurt, C., Jones, T. M., & Evans, M. (2019). Deintensification of Adjuvant Treatment After Transoral Surgery in Patients With Human Papillomavirus-Positive Oropharyngeal Cancer: The Conception of the PATHOS Study and Its Development. Frontiers in Oncology, 9. doi:10.3389/fonc.2019.00936

    Rachel J. Carter; Mateus Milani; Michael Butterworth; Ahoud Alotibi; Nicholas Harper; Govindaraju Yedida; Georgia Greaves; Aoula Al-Zebeeby; Andrea L. Jorgensen; Andrew G. Schache; Janet M. Risk; Richard J. Shaw; Terry M. Jones; Joseph J. Sacco; Adam Hurlstone; Gerald M. Cohen; Shankar Varadarajan (2019). Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death & Disease, 10. doi:10.1038/s41419-019-2150-8

    Earnshaw, C. H., Kinshuck, A. J., Loh, C., Tandon, S., Jackson, S. R., Jones, T. M., & Lancaster, J. (2019). An audit of fifty patients receiving Artiss (TM) fibrin sealant in lateral selective neck dissections. Clinical Otolaryngology. doi:10.1111/coa.13485

    Masterson, L., Lechner, M., & Jones, T. M. (2019). Targeting mTOR in Head and Neck Cancer-Letter. Clinical Cancer Research, 25(21), 6554. doi:10.1158/1078-0432.CCR-19-1079

    Stephanie G. Craig, Lesley A. Anderson, Andrew G. Schache, Michael Moran, Laura Graham, Keith Currie, Keith Rooney, Max Robinson, Navdeep S. Upile, Rachel Brooker, Mina Mesri, Victoria Bingham, Stephen McQuaid, Terry Jones, Dennis J. McCance, Manuel Salto-Tellez, Simon S. McDade & Jacqueline A. James (2019) Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach. British Journal of Cancer, 120, 827–833


    Wilkie MD, Lau AS, Vlatkovic N, Jones TM, Boyd MT. (2018) Metabolic signature of squamous cell carcinoma of the head and neck: Consequences of TP53 mutation and therapeutic perspectives. Oral Oncol. 2018 Aug;83:1-10. doi:

    10.1016/j.oraloncology.2018.05.018. Epub 2018 Jun 2. Review. PubMed PMID: 30098763.

    Lechner M, Chakravarthy AR, Walter V, Masterson L, Feber A, Jay A, Weinberger PM, McIndoe RA, Forde CT, Chester K, Kalavresos N, O`Flynn P, Forster M, Jones TM, Vaz FM, Hayes DN, Fenton TR. (2018) Frequent HPV-independent p16/INK4A overexpression in head and neck cancer. Oral Oncology, 83, 32-37. doi:10.1016/j.oraloncology.2018.06.006

    Christian Grønhøj, David H. Jensen, Christian Dehlendorff, Linda Marklund, Steffen Wagner, Hisham Mehanna, Eva Munck-Wikland, Torbjörn Ramqvist, Anders Näsman, Claus Wittekindt, Nora Würdemann, Shachi Jenny Sharma, Stefan Gattenlöhner, Katalin Kiss, Elo Andersen, Rachel Spruce, Nikos Batis, Max Robinson, Kevin Harrington, Stuart Winter, Terence M Jones, Jens Peter Klussmann, Tina Dalianis, Jeppe Friborg, and Christian von Buchwald  (2018). Development and external validation of nomograms in oropharyngeal cancer patients with known HPV-DNA status: a European Multicentre Study (OroGrams). British Journal of Cancer, 118(12), 1672-1681. doi:10.1038/s41416-018-0107-9

    B G Taib, J Oakley, Y Dailey, I Hodge, P Wright, R du Plessis, J Rylands, D Taylor-Robinson, S Povall, A Schache, R Shaw, A Dingle & T M. Jones (2018) Socioeconomic Deprivation and the Burden of Head and Neck Cancer- Regional variations of Incidence and Mortality in Merseyside and Cheshire, North West, England.  Clinical Otolaryngology 43 (3). 846 - 853



    Povall S, Taib B, Jones T, & Taylor-Robinson D. (2017) Socioeconomic inequalities in head and neck cancer outcomes, a scoping literature review: Preliminary findings. European Journal of Surgical Oncology, 43(11), 2235. doi:10.1016/j.ejso.2017.10.174

    Ghazali N, Roe B, Lowe D, Tandon S, Jones TM, Brown JS, Shaw RJ, Risk JM & Rogers SN.(2017) Using the Patients Concerns Inventory for Distress Screening in Post-treatment Head and Neck Cancer Survivors.  Journal of Cranio-Maxillofacial Surgery 45 (10), 1743-1748

    Screening for distress using the distress thermometer and the University of Washington Quality of Life in post-treatment head and neck cancer survivors.Ghazali, N , Roe, B , Lowe, D , Tandon, S , Jones, T , Brown, J , Shaw, R , Risk, J and Rogers, SN (2017)  European Archives of Oto-Rhino-Laryngology, 274 (5). 2253 - 2260. ISSN 0937-4477, 1434-4726

    The cost of oropharyngeal cancer in England: A retrospective hospital data analysis. Keeping ST, Tempest MJ, Stephens SJ, Carroll SM, Simcock R, Jones TM & Shaw RJ. Clin Otolaryngol. 2017;00:1-7.

    Protocol: systematic review of the association between socio-economic status and survival in adult head and neck cancer. Taib, B. G., Rylands, J., Povall, S., Jones, T. M., & Taylor-Robinson, D. (2017). Systematic Reviews6, 151.

    Voice outcomes for early laryngeal cancer. Current Opinion in Otolaryngology & Head and Neck Surgery. 25(3):211-216, JUN 2017 Andrew J Kinshuck; Aditya Shenoy; Terence M Jones DOI: 10.1097/MOO.0000000000000363